Ageing is closely linked to mitochondrial decline. Boosting NAD⁺ levels and supplementing with AKG have shown strong potential to improve mitochondrial function by activating SIRT1 and regulating PCG-1α and HIF-1α pathways.

ECA’s R&D team developed NRAKG, a unique bonded compound of NR and AKG. Unlike a simple blend, this structure significantly enhances SIRT1 gene expression in zebrafish, outperforming the physical mix of NRCl and calcium-AKG.

With its superior bioactivity, Senolyte™ NRAKG is a next-gen ingredient for brands targeting healthy aging, cellular energy, and mitochondrial wellness.